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. Author manuscript; available in PMC: 2006 Oct 30.
Published in final edited form as: Nat Neurosci. 2005 Mar 6;8(4):476–483. doi: 10.1038/nn1419

Figure 2.

Figure 2

A reduced proportion of Vip−/− and Vipr2−/− SCN neurons fires rhythmically in vitro. (a) Representative firing rate traces showing examples of circadian and arrhythmic neurons from each genotype. The χ2 periodogram to the left of each plot shows the period estimation of each neuron as in Figure 1. (b) The percentage of SCN neurons with a circadian firing pattern was reduced for both mutants relative to wild-type. (c) The circadian amplitudes (mean ± s.e.m.) of mutant rhythms were lower than in the wild type. Asterisk (*) indicates P < 0.0005, one-way ANOVA with Scheffé post hoc test.