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Effect of PAR-2AP administration on heart damage evaluated as CK release over reperfusion. PAR-2AP dose dependently reduces total integrated CK during reperfusion. Genistein did not revert PAR-2AP effect. Trypsin caused a small but significant reduction of CK release over reperfusion comparable to the lower dose of PAR-2AP used. Data are expressed as mean ± SD, n = 6; *P < 0.05, **P < 0.01 vs. control and scrambled peptide.
