Table 2.
Glutathione peroxidase, mU/mg prot | Glutathione reductase, mU/mg prot | Mn-superoxide dismutase, units/mg prot | |
---|---|---|---|
Control nonischemic hearts | 86.7 ± 4.5† | 2.5 ± 0.2 | 2.4 ± 0.4 |
Control ischemic hearts | 59.8 ± 6.8 | 2.8 ± 0.2 | 2.1 ± 0.2 |
Scrambled-treated ischemic hearts | 60.8 ± 6.5 | 2.6 ± 0.2 | 2.0 ± 0.2 |
100 μM PAR-2AP-treated ischemic hearts | 65.7 ± 7.5 | 2.7 ± 0.2 | 3.2 ± 0.4‡ |
30 μM PAR-2AP-treated ischemic hearts | 63.8 ± 8.6 | 2.6 ± 0.2 | 2.8 ± 0.3* |
10 μM PAR-2AP-treated ischemic hearts | 63.4 ± 7.9 | 2.5 ± 0.2 | 2.4 ± 0.4 |
100 μM PAR-2AP + genistein-treated ischemic hearts | 67.8 ± 8.2 | 2.7 ± 0.2 | 2.8 ± 0.4* |
†, P < 0.05 vs. control ischemic hearts; *, P < 0.05 vs. scrambled and control ischemic hearts; ‡, P < 0.05 vs. scrambled and control ischemic hearts. Mean ± SD, n = 6 for each group.