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. 2000 Mar 21;97(7):3684–3689. doi: 10.1073/pnas.060590697

Figure 3.

Figure 3

BRET as a sensor for biological processes in vivo. (A) Schematic representation of the Rluc-YFP fusion construct harboring a consensus cleavage site (DEVD) for caspase-3. (B) The BRET ratio measured in cells expressing the fusion protein treated or not with staurosporine and/or the caspase-3 inhibitor-I. The data shown represent the mean ± SEM of four independent readings.