Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Whole cell competition binding studies for [3H]estradiol in the PCY2 yeast. (A) E2 and tamoxifen. The curves are as follows: E2 (●); tamoxifen (■). The Ki values are 3.47 ± 0.12 nM for E2 and 2.61 ± 0.19 μM for tamoxifen. (B) ICI 182,780. The ED50 for increasing [3H]estradiol binding was 52.3 ± 12.4 μM. The curves are representative of three to four independent experiments, with compound concentrations run in quadruplicate. The points shown are means ± SEM.
