. 2006 Aug 25;91(10):3653–3663. doi: 10.1529/biophysj.106.092510

TABLE 1.

Velocity-dependent rate functions used in some transitions within the cross-bridge cycle

Transition/state	k_i (s⁻¹)	Function	Function parameters
0-1	40	k/k_i = 1 (for single hyperbolic curve)
0-1	40	k/k_i = 0.5 + a(1−e^−b(V/Vmax)) (for curvature reversal at low V only)	a = 1.2; b = 22
0-1	40	k/k_i = e^−c(V/Vmax) + e^d(V/Vmax) −1 (for double hyperbolic curve only, maximum value of k/k_i is capped at 1.4)	c = 20; d = 7
1-0	70	k/k_i = 1 + m(V/V_max)	m = 70
1-2	140	k/k_i = 1 + m(V/V_max)	m = 14
2-3	150	k/k_i = 1 + m(V/V_max)	m = 14
3-4	20	k/k_i = 1 + m(V/V_max)	m = 14
4-5	20	k/k_i = 1 + m(V/V_max)	m = 14
5-6	10	k/k_i = 1 + m(V/V_max)	m = 14
6-0	20	k/k_i = 1 + m(V/V_max)	m = 14
2	—	F/F_i = 1 − n(V/V_max)	n = 0.57
3	—	F/F_i = 1 − n(V/V_max)	n = 0.57
4	—	F/F_i = 1 − n(V/V_max)	n = 0.86
5	—	F/F_i = 1 − n(V/V_max)	n = 1.43
6	—	F/F_i = 1 − n(V/V_max)	n = 1.43

Note: Transitions not listed in the table are velocity-independent and the rate constants are listed in Fig. 1 legend.