TABLE 2.
Summary of changes in force, velocity, and curvature in simulation of the effects of ↓[ATP], ↑[ADP], and ↑[Pi ]
Transition rate change | (Fmax)t/(Fmax)c | (Vmax)t/(Vmax)c | (a/Fmax)t/(a/Fmax)c |
---|---|---|---|
(k60)t/(k60)c = 0.1 (↓[ATP]) | 1.237 | 0.788 | 2.650 |
(k56)t/(k56)c = 0.2 (↑[ADP]) | 1.240 | 0.856 | 1.746 |
(k23)t/(k23)c = 0.2 (↑[Pi]) | 0.718 | 1.000 | 1.505 |
Note: The subscripts c and t denote control and test, respectively. The control parameters are derived from the force-velocity curve shown in Fig. 3 that possesses initial k values as indicated in Fig. 1 legend. The only change made to produce a test curve (shown in Fig. 6) is by changing one transition rate as indicated by the ratios listed in the first column of this table.