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. 2006 Aug 25;91(10):3653–3663. doi: 10.1529/biophysj.106.092510

TABLE 2.

Summary of changes in force, velocity, and curvature in simulation of the effects of ↓[ATP], ↑[ADP], and ↑[Pi ]

Transition rate change (Fmax)t/(Fmax)c (Vmax)t/(Vmax)c (a/Fmax)t/(a/Fmax)c
(k60)t/(k60)c = 0.1 (↓[ATP]) 1.237 0.788 2.650
(k56)t/(k56)c = 0.2 (↑[ADP]) 1.240 0.856 1.746
(k23)t/(k23)c = 0.2 (↑[Pi]) 0.718 1.000 1.505

Note: The subscripts c and t denote control and test, respectively. The control parameters are derived from the force-velocity curve shown in Fig. 3 that possesses initial k values as indicated in Fig. 1 legend. The only change made to produce a test curve (shown in Fig. 6) is by changing one transition rate as indicated by the ratios listed in the first column of this table.