Evolutionary conservation as a powerful criterion for screening
computationally derived basonuclin target candidates. (A) A
comparison of basonuclin zinc fingers in some of the vertebrates.
The amino acid sequences of the three pairs of basonuclin zinc
fingers (ZF12, ZF34 and ZF56) from human (hBsn), chimpanzee (pBsn), mouse
(mBsn), domestic dog(cBsn), cow(bBsn), fowl(gBsn) and zebrafish (dBsn) are
align. The cystines and histidines are in bold and the amino acid
substitutions are highlighted in yellow. (B) The enrichment of
basonuclin target candidates during each step of screening. The results from
screening two databases (Ensembl and DBTSS) are shown and the data are
listed in Table 1.