Table 6.

Relationship between the histopathological grades and the presence of trisomy 18 as revealed by fluorescence in situ hybridization

	No. of patients				No. of patients
	trisomy 18 (+)	trisomy 18 (-)	p-value		trisomy 18 (+)	trisomy 18 (-)	p-value
plasma cells				brown-pigment-laden histiocytes
2+, 3+	2	6	0.153	(-)	7	10	0.366
2+ <	14	12		(+)	9	8
Dutcher bodies				mitotic cells
(-)	10	11	0.607	(-)	0	4	0.066
(+)	6	7		(+)	16	14
monocytoid B cells				nodularity
(-)	1	5	0.116	(-)	6	1	0.029
(+)	15	13		(+)	10	17
residual reactive germinal centers				lymphoepithelial lesions *
(-)	1	6	0.061	(-)	0	4	0.049
(+)	15	12		(+)	6	3
large lymphoid cells				reactive T cells **
2+	2	6	0.153	1+	12	10	0.183
(-), 1+	14	12		2+	3	7
polykaryocytes
(-)	5	7	0.459
(+)	11	11

* 21 cases (10 trisomy 18 (+), 11 trisomy 18 (-)) were not applicable.

** Two cases (one trisomy 18 (+), one trisomy 18 (-)) were not done.