Table I.
Peak change in membrane potential induced by 1,000 μM of the six potent amino acids or glutathione in wild type and glr3.3 mutants
Values shown are the mean peak change in mV ± SEM.
| Genotype | Amino Acids
|
Glutathione
|
||||||
|---|---|---|---|---|---|---|---|---|
| Ala | Asn | Cys | Glu | Gly | Ser | GSH | GSSG | |
| Wild type | 117 ± 11 | 87 ± 7 | 91 ± 1 | 83 ± 5 | 98 ± 8 | 90 ± 12 | 104 ± 15 | 43 ± 3 |
| (n = 3) | (n = 3) | (n = 4) | (n = 8) | (n = 7) | (n = 3) | (n = 7) | (n = 10) | |
| glr3.3-1 | 46 ± 13 | 41 ± 3 | 45 ± 3 | 38 ± 2 | 47 ± 4 | 47 ± 4 | 19 ± 6 | 22 ± 3 |
| (n = 4) | (n = 5) | (n = 3) | (n = 7) | (n = 6) | (n = 3) | (n = 4) | (n = 5) | |
| glr3.3-2 | 41 ± 3 | 50 ± 4 | 40 ± 2 | 44 ± 6 | 38 ± 5 | 43 ± 6 | 31 ± 4 | 18 ± 4 |
| (n = 3) | (n = 3) | (n = 3) | (n = 7) | (n = 6) | (n = 3) | (n = 4) | (n = 4) | |