Growth inhibition of T. brucei bloodstream form (Left) and T. cruzi amastigotes in 3T3 host cells (Middle) in the presence of adenosine (■) and GAPDH inhibitors 5 (▵), 7 (▾), and 8 (○). Pyruvate production in bloodstream T. brucei after addition of 0 (○), 12 (▴), 24 (▵), and 40 μM (●) 8 (Right) (▵ and ● overlap in parts).