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. 1977 Nov 26;2(6099):1381–1384. doi: 10.1136/bmj.2.6099.1381

Cervical ripening with intravaginal prostaglandin E2 gel.

I Z MacKenzie, M P Embrey
PMCID: PMC1632392  PMID: 338109

Abstract

We describe a technique of administering prostaglandin E2 (PGE2) in a viscous cellulose gel into the vagina to ripen the unfavourable cervix in patients requiring induction of labour. A total of 168 primigravidae were studied, of whom 102 received 2 mg PGE2 in 2% gel and 66 received 5 mg PGE2 in 4% gel. In the latter group, the state of the cervix was significantly improved in 58 patients (87.9%), while 32 (48.5%) had started labour before planned induction. There were no maternal or fetal side effects or complications.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Calder A. A., Embrey M. P., Tait T. Ripening of the cervix with extra-amniotic prostaglandin E2 in viscous gel before induction of labour. Br J Obstet Gynaecol. 1977 Apr;84(4):264–268. doi: 10.1111/j.1471-0528.1977.tb12574.x. [DOI] [PubMed] [Google Scholar]
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