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Lack of shape complementarity in the presumptive complex of CD58 and CD2. (A) Two orthogonal views of cCD58 (red) and human sCD2 (blue) docked according to the orthogonal homodimeric human sCD2 crystal lattice contacts (9). (B) The region boxed in A is enlarged, and the solvent-accessible molecular surfaces of central sections of the interacting β-sheets of CD58 and CD2 are depicted semitransparently.
