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. 2006 Summer;5(2):99–103. doi: 10.1187/cbe.06-02-0148

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© 2006 by The American Society for Cell Biology

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Figure 2. — A dorsal view of three neurulating Xenopus embryos between the midneural stage 16 (A) and the neural tube stage 21 (C). The embryo on the left is expressing Xdd1, an injected mutant form of Dishevelled and fails to close its tube (open-NT). The middle embryo is also expressing Xdd1 but successfully closes its neural tube (closed-NT) while lagging behind the control. The embryo on the right is an uninjected control. The arrows indicate neural folds in various degrees of closure. Although only relative developmental times are provided (in the form of “stages”), the same population of embryos was subdivided, with one receiving an injection of mutant Xdd1 and the other behaving as an uninjected control; both subpopulations were reared under identical conditions. The time elapsed in A–C is approximately four hours. The entire video may be viewed at http://dev.biologists.org/content/vol129/issue24/images/data/5815/DC1/MOVIE1.mov.