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. Author manuscript; available in PMC: 2006 Nov 6.
Published in final edited form as: Ann N Y Acad Sci. 2006 Apr;1068:297–308. doi: 10.1196/annals.1346.057

FIGURE 2.

FIGURE 2

The osteoclastogenic effect of AZT in PBMCs. PBMCs (2 × 106 PBMCs per well) from two HIV-positive, HAART-naïve patients and six age-, sex-matched HIV-negative individuals were cultured with RANKL alone (R), or RANKL plus AZT (R+A) in the presence of M-CSF for 2 weeks. Treatment with M-CSF alone was a control (C). The number of multinucleated TRAP positive osteoclasts were counted. The results of the Student's t-test are indicated.