Fig. 1.
Effects of hMSCs on blood glucose and mouse insulin levels in STZ-induced diabetic NOD/scid mice. (A) Blood glucose levels in untreated diabetic mice (STZ) and in hMSC-treated diabetic mice (STZ + hMSCs). Values are mean ± SE from three experiments. (B) Blood glucose levels in untreated diabetic mice and diabetic mice infused with human fibroblasts (STZ + hFibroblasts). Differences on day 10 reflect variations in untreated mice before fibroblasts were infused. Values are mean ± SD. (C) Blood levels of mouse insulin on day 32 in diabetic mice (STZ), hMSC-treated diabetic mice (STZ + hMSCs), and normal mice. Values are mean ± SD. ∗, Values that differ from each other with P = 0.0018.