Table 2.
African-American n (%) | Caucasian n (%) | p-value2 | Combined n (%) | |
C677T | ||||
C/C | 114 (81) | 49 (48) | < 0.001 | 163 (67) |
C/T | 27 (19) | 44 (43) | 71 (29) | |
T/T | 0 | 9 (9) | 9 (4) | |
A1298C | ||||
A/A | 98 (69) | 37 (36) | < 0.001 | 135 (56) |
A/C | 38 (27) | 49 (48) | 87 (36) | |
C/C | 5 (4) | 16 (16) | 21 (8) |
1 Only cases who were successfully genotyped for both SNPs (n = 243) are included
2 Chi-square test comparing genotype distributions between African-Americans and Caucasians