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. 2006 Nov 7;4(11):e369. doi: 10.1371/journal.pbio.0040369

Figure 2. The PGC1βKO Mouse Has Altered Metabolism under Standard Environmental Conditions.

Figure 2

(A) Growth curves of male (left panel) and female (right panel) mice on normal diet. WT (solid circles) and PGC1βKO (open circles) mice, n = 18–21 mice per group.

(B) Assessment of fat content by DEXA in 8- and 32-wk-old male WT (solid bars) and PGC1βKO mice (open bars), n = 8–12 mice per group.

(C) Representative histological sections of tissues from WAT (n = 6).

(D) Size distribution of adipocytes from WT and PGC1βKO mice. Two fields from each section from epididymal adipose tissue depot (n = 4 mice per genotype) were analysed to obtain the mean cell area per animal.

(E) Epididymal WAT gene expression from 12-wk-old PGC1βKO (white bars) and WT littermates (black bars). Individual measurements are standardized using 18S, and then the average of the WT group was set to 1. n = 5–8 mice per group.