Table 1.
Effect of tamoxifen on organellar pH
| Cytosol | Nucleus | Recycling endosomes | Lysosomes | |
|---|---|---|---|---|
| MCF-7/ADR | 7.10 ± 0.1 | 7.20 ± 0.1 | 6.1 ± 0.2 | 5.2 ± 0.1 |
| + Tamoxifen | 7.20 ± 0.1 | 7.20 ± 0.1 | 6.7 ± 0.2 | 6.6 ± 0.1 |
| Change | +0.1 | 0.0 | +0.6 | >+1.4 |
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