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. 2006 Sep 5;50(11):3717–3723. doi: 10.1128/AAC.00460-06

TABLE 3.

Norfloxacin resistance of E. coli TG1ΔacrAB expressing mutant NorM proteinsa

NorM mutant NOR MIC (μg/ml)
Vector alone 0.016
Wild type 1
E2V 0.5
E11V 1
D36V 1
D47V 0.5
E91V 0.5
D121V 0.5
E123V 0.5
E124V 0.063
D155V 0.063
Δ[G184KFGAP189] 0.016
G184V 0.016
G184W 0.016
G184A 0.5
K185I 0.0156
K185R 1
G187V 0.25
G187R 0.063
G187A 1
P189S 0.016
E190K 0.016
E190A 0.016
E190V 0.016
E190D 1
G192V 0.5
G195V 1
C196S 0.125
E228V 0.5
E237V 0.5
E255V 0.5
G270V 1.0
E308V 0.5
D310V 0.5
C330S 1
E341V 0.5
E349V 0.5
C369S 1
D371V 0.5
L381P 1
R382G 1
G383V 1
Y384F 0.125
Y384H 0.063
Y384S 0.25
K385I 0.5
D386V 0.5
M387I 1
E417V 0.5
D452V 1
D453V 0.5
a

All experiments were carried out thrice with the same results.