TABLE 1.

Study subjects^a

Subject no.	Sample no.	Sample day	MIC(s) (μg/ml)	Mutation(s) in:		OSTd	PFGE pattern(s)
				gyrA	parC
1	1	0	70.25	A87T	None	Neg	A
	2	28	0.25	A87T	None	Pos	A
	3	41	Neg
	4	57	Neg
	5
	6
	7
	8
	9
	10
2	1	0	0.5	S83L	Neg	Neg	B
	2	58	Neg
	3	71	Neg
	4	85	Neg
	5	99	Neg
	6	119	Neg
	7	176	Neg
	8
	9
	10
3	1	0	32	S83L, D87G	S80I	Pos	C
	2	17	Neg
	3	28	Neg
	4	44	Neg
	5	57	32	S83L, D87G	S80I	Pos	C
	6	71	Neg
	7	85	32	S83L, D87G	S80I		C
	8	100	Neg
	9	128	0.064	Neg	Neg	Pos	D
	10	156	Neg
4	1	0	0.19	Neg	Neg	Neg	E
	2	17	Neg
	3	35	Neg
	4	45	Neg
	5	60	Neg
	6	72	Neg
	7	92	Neg
	8	102	0.064	Neg	Neg	Neg	E
	9	140	Neg
	10	178	Neg
5	1	0	>32	S83L, D87T	S83L, D87T	Pos	F
	2	17	>32	S83L, D87T	S83L, D87T	Pos	F
	3	29	>32	S83L, D87T	S83L, D87T	Pos	F
	4	38	>32	S83L, D87T	S83L, D87T	Pos	F
	5	58	>32	S83L, D87T	S83L, D87T	Pos	F
	6	71	>32	S83L, D87T	S83L, D87T	Pos	F
	7	85	>32	S83L, D87T	S83L, D87T	Pos	F
	8	112	>32	S83L, D87T	S83L, D87T	Pos	F
	9	139	>32	S83L, D87T	S83L, D87T	Pos	F
	10	167	>32	S83L, D87T	S83L, D87T	Pos	F
6	1	0	32	S83L, D87D	S80I, G84V	Pos	NT
	2	12	32	S83L, D87D	S80I, G84V	Pos	NT
	3	27	32/32b	S83L, D87D	S80I, G84V	Neg/neg	NT
	4	41	32	S83L, D87D	S80I, G84V	Pos	NT
	5	56	32	S83L, D87D	S80I, G84V	Neg	NT
	6	70	Neg
	7	83	32	S83L, D87D	S80I, G84V	Pos	NT
	8	134	Neg
	9	153	32	S83L, D87D	S80I, G84V	Pos	NT
	10
				gyrA	parC
7	1	0	0.25	D87T	Neg	Neg	G
	2	12	0.25	D87T	Neg	Neg	G
	3	26	Neg
	4	41	Neg
	5	56	Neg
	6	70	0.25	D87T	Neg	Neg	G
	7	84	0.25	D87T	Neg	Neg	G
	8	106	0.38	D87T	Neg	Neg	G
	9	132	NA	NA	NA	NA	NA
	10	162	0.19	D87T	Neg	Neg	G
8	1	0	0.19	Neg	Neg	Pos	H
	2	28	Neg
	3	37	0.38	Neg	Neg	Pos	H
	4	51	0.25	Neg	Neg	Pos	H
	5	65	0.125	Neg	Neg	Pos	H
	6	79	0.125	Neg	Neg	Pos	H
	7	94	0.19	Neg	Neg	Pos	H
	8	107	0.19	Neg	Neg	Pos	H
	9	141	Neg
	10	177	Neg
9	1	0	>32	S83L, D87N	S80I	Pos	I
	2	21	>32	S83L, D87N	S80I	Pos	I
	3	34	0.5	S83L	Neg	Neg	J
	4	50	0.5	S83L	Neg	Neg	J
	5	64	>32/0.5c	S83L, A87Nc	S80Ic	Pos/negc	I/J
	6	92	>32	S83L, D87N	S80I	Pos	I
	7	99	0.5	S83L	Neg	Neg	J
	8	112	0.19	S83L	Neg	Neg	J
	9	146	>32	S83L, D87N	S80I	Pos	I
	10	173	>32	S83L, D87N	Neg	Pos	I
10	1	0	0.38	D87N	Neg	Neg	K
	2	38	0.38	D87N	Neg	Neg	K
	3	53	0.38	D87N	Neg	Neg	K
	4	66	0.38	D87N	Neg	Neg	NA
	5	80	0.38	D87N	Neg	Neg	K
	6	95	0.25	D87N	Neg	Neg	K
	7	127	0.10	D87N	Neg	Neg	K
	8	148	Neg
	9
	10

^aSample no. 1 represents the final inpatient sample; sample day refers to the number of days after discharge the sample was obtained. There was no genetic relatedness of isolates across subjects. Neg, negative; Pos, positive; NA, not available; NT, not typeable.

^bTwo strains identified differed only in that one strain had the noted parC mutations while the other strain had no parC mutations.

^cThe MIC values, gyrA and parC mutations, and the OST findings were consistent with both previously identified strains in this patient.

^dOST, organic-solvent tolerance.