FIG. 3.

Mean (± standard deviation) levofloxacin (upper panels) and ciprofloxacin (lower panels) plasma concentrations (μg/ml) on days 2, 6, 11, 21, and 31 (i.e., 1, 5, 10, 20, and 30 days of drug treatment) of the study (left panels, females; right panels, males). Monkeys were treated with levofloxacin (at 15/4 mg/kg) or ciprofloxacin (at 16 mg/kg twice a day) following aerosol challenge with B. anthracis on day 1. Open and closed symbols represent the data after the first and second daily dose, respectively. Values below the lower limit of quantification are not shown in the figure.