TABLE 5.
Monkey | Sex | Ames LD50 equivalent | Day(s) postchallenge with positive blood cultures | Day of death postchallenge |
---|---|---|---|---|
Vehicle group | ||||
3988 | M | 30 | 2, 3 | 3 |
4174 | M | 22 | 2, 3 | 3 |
4813 | M | 32 | 2 | 2 |
4004 | M | 76 | 2, 3, 5-7 | 7 |
4115 | M | 118 | 2 | —a |
4501 | F | 17 | 1, 2, 4 | 8 |
4758 | F | 20 | 2, 3 | 3 |
4985 | F | 27 | 2, 4 | 4 |
4785 | F | 48 | 2, 3, 4 | 4 |
4944 | F | 47 | 2, 3, 4 | 4 |
Levofloxacin group | ||||
4010 | M | 17 | —b | —a |
4039 | M | 54 | —b | —a |
5026 | M | 65 | —b | —a |
4998 | M | 57 | —b | —a |
5003 | M | 59 | —b | —a |
4979 | F | 55 | —b | —a |
4744 | F | 62 | —b | —a |
4491 | F | 50 | 38 | 38 |
4957 | F | 36 | —b | —a |
4941 | F | 34 | —b | —a |
Ciprofloxacin group | ||||
4211 | M | 68 | 53, 55, 57 | 57 |
4180 | M | 99 | —b | —a |
4031 | M | 53 | —b | —a |
4040 | M | 24 | —b | —a |
5025 | M | 36 | —b | —a |
4745 | F | 67 | —b | —a |
4742 | F | 44 | —b | —a |
4983 | F | 45 | 66 | 66 |
4949 | F | 21 | —b | —a |
4670 | F | 99 | —b | —a |
The monkey survived to end of observation period (100 days).
Indicates no positive blood cultures.