TABLE 1.
Study isolates
Isolate | 5FC MIC (mg/liter)a | Amino acid at position 101b | Interpretation of genotype |
---|---|---|---|
F/10141 | 0.06 | Arg | Homozygous susceptible |
F/6862 | 0.125 | Arg | Homozygous susceptible |
F/7421 | 0.5 | Arg/Cys | Heterozygous |
F/9651 | 4 | Arg | Homozygous susceptible, unknown mechanism of elevated MIC |
F/9464 | 8 | Cys | Homozygous resistant |
F/8341 | >64 | Cys | Homozygous resistant |
Determined using EUCAST methodology.
Polymorphisms within the protein uracil phosphoribosyltransferase.