Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model for the regulation of Msx2 expression by Dlx2, Lef-1 and Msx2. Dlx2 activates the Msx2 promoter and can synergistically activate Msx2 in concert with Lef-1. Msx2 can repress Dlx2 activation through competition for shared DNA-binding sites on the Msx2 promoter or direct protein interactions. Msx2 can negatively auto-regulate its promoter, shown by the large arrow.
