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. 2006 Oct 27;400(Pt 1):23–32. doi: 10.1042/BJ20060897

Figure 1. Schematic representation of human CHMP7 and comparison with other CHMP family proteins.

Figure 1

(A) Domain structure of CHMP7. CHMP7 contains an SNF7 domain (CDD accession number pfam03357) which is found in a group of Snf7 homologues, including ESCRT-III components. The N-terminal half also has a sequence related to the SNF7 domain, indicated by a grey bar (SNF7-related domain). CCs predicted by using a program on the Internet (http://www.ch.embnet.org/software/COILS_form.html; window 21, score above 0.2), are indicated by large closed boxes. Clusters of basic and acidic residues are indicated by small closed and open boxes respectively. Amino acid sequence alignments between CHMP7NH (amino acids 1–222) and CHMP4b (B) and between CHMP7CH (amino acids 223–429) and CHMP6 (C). Alignment was performed by using a pairwise alignment program, EMBOSS-Align. Identical and similar residues are shaded dark grey and light grey.