Fig. 6: Region of interest analyses. Activation of Wernicke's area (note black regions of interest [ROIs] in the cortex) in the subgroup without auditory verbal hallucination (AVH) was significantly different from that of healthy control subjects and the AVH subgroup (A). The AVH subgroup had higher baseline activity (nonsignificant) in Wernicke's area than both the NAVH and the healthy control groups. This could be related to an ongoing experience of verbal hallucinations. Activation of Broca's area (note black ROIs in the cortext) was not different across the 3 groups (B). Both the healthy control subjects and the NAVH groups showed higher activity in the left SMA than in the right SMA (note black ROI and white ROI at midline) (C). The inverse is true in the AVH group.