Mean serum enzyme activity and ion concentrations for the 40 animals. The asterisk indicates a significant difference (P < 0.05) between the control and treated groups. Different lower-case letters (a,b,c,d; x,y,z,w) indicate significant differences (P < 0.05) between means in the control group and in the treated group, respectively. ALT — alanine aminotransferase; AST — aspartate aminotransferase; CK — creatine kinase; LDH — l-lactate dehydrogenase.