Figure 2.

CGH profile of a single peripheral blood leukocyte of a male patient with Down’s syndrome. To be considered significant, deviations from the central line had to cross the green (chromosomal gain) or red (chromosomal loss) punctate line. The gray shaded horizontal bars indicate regions excluded from analysis because of the prevalence of heterochromatic DNA. The chromosome 21 (except of the blocked heterochromatic region) was found to be amplified entirely whereas all other chromosomes showed normal profiles.