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. Author manuscript; available in PMC: 2006 Nov 14.
Published in final edited form as: J Neurochem. 2003 Aug;86(3):545–555. doi: 10.1046/j.1471-4159.2003.01812.x

Table 3.

Effect of Rofecoxib and Valeryl salicylate on the spontaneous and iron-catalyzed peroxidation of rat brain phospholipids.

Spontaneous Peroxidation
 Iron-catalyzed Peroxidation
Sample λ=532 nm Inhibition (%) Sample λ=532 nm Inhibition (%)
Blank 0.362 - Blank 0.559 -
Rofecoxib 100 μM 0.291 19 Rofecoxib 100 mM 0.545 2
Rofecoxib 1mM 0.407 0 Rofecoxib 1mM 0.556 0
Rofecoxib 2mM 0.383 0 Rofecoxib 2mM 0.573 0
VAS 100 μM 0.304 16 VAS 100 μM 0.614 0
VAS 1 mM 0.361 0 VAS 1 mM 0.628 0
VAS 2 mM 0.137 62 VAS 2 mM 0.526 6

Results represent the extent of lipid peroxidation as measured by thiobarbituric acid reactive substances (TBARS) at a wavelength of 532 nm. See Aruoma et al., 1992 for details.