FIG. 1.

Central carbon metabolism and intermediates from primary metabolism for Act production in S. coelicolor. G6P, glucose-6-phosphate; F6P, fructose-6-phosphate; F1,6DP, fructose-1,6-diphosphate; GAP, glyceraldehyde-3-phosphate; 1,3 BPG, 1,3-diphosphoglycerate; 3PG, 3-phosphoglycerate; 2PG, 2-phosphoglycerate; PEP, phosphoenolpyruvate; 6PGL, 6-phosphoglucolactone; 6PG, 6-phosphogluconate; Ru5P, ribulose-5-phosphate; Ri5P, ribose-5-phosphate; Xu5P, xylulose-5-phosphate; SHu7P, sedoheptulose-7-phosphate; E4P, erythrose-4-phosphate; HK, hexokinase; Pfk, phosphofructokinase; Adl, aldolase; Tpi, triose phosphate isomerase; Gpdh, glyceraldehyde-3-phosphate dehydrogenase; Pgk, phosphoglycerate kinase; Pgm*, phosphoglycerate mutase; Eno, enolase; Pyk, Pyruvate kinase; Pdh, pyruvate dehydrogenase; ACCase, acetyl-CoA carboxylase; Zwf, glucose-6-phosphate dehydrogenase; Pgm, phosphoglucomutase; Pgl, phosphoglucolactonase; Pgdh, phosphogluconate dehydrogenase; Ppi, phosphopentose isomerase; Tkl, transketolase; Tal, transaldolase.