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. 2006 Aug 26;34(16):4354–4363. doi: 10.1093/nar/gkl443

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© 2006 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(A) Plot of the melting temperatures of [p(C₅T)]₄, [d(TC₅)]₄ and hybrid tetraplexes, at 25 μM strand concentration, as a function of pH. The lines merely serve as a visual aid. (B) CD profiles of the hybrid, [p(C₅T)]₄, [d(TC₅)]₄ tetraplexes at 12.5 μM strand concentration at pH 4.5. Inset shows CD at 288 nm as a function of varying PNA concentration with DNA concentration were fixed at 10 μM.