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. 2006 Aug 31;34(16):4458–4466. doi: 10.1093/nar/gkl587

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© 2006 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Enzymatic digesion analysis of an oligonucleotide containing a G-T ICL. (A) HPLC profile of oligonucleotide 6 following enzymatic digestion and dephosphporylation. The four nucleosides and fluorescent label 6-FAM are indicated. (B) HPLC profile of ICL-containing oligonucleotide 10 after enzymatic digestion and dephosphorylation. The peak for the crosslinked T-G residue is denoted by an arrow (C) HPLC profiles of the T(N3)-dG(N1) dimer 14 and the T(N3)-dG(O6) dimer 18.