Table 3.

Structural statistics for the Bcl2Mid^a

NMR distance and dihedral constraints
Distance restraints
Total NOE	476
Intraresidue	309
Interresidue	167
Sequential (|i − j| = 1)	107
Non-sequential (|i − j| > 1)	60
Hydrogen bonds	26
Total dihedral angle restraints	38
Structure statistics
Violations (mean and s.d.)
Distance constraints (Å)	0.03 ± 0.003
Dihedral angle constraints (°)	0.81 ± 0.63
Max. dihedral angle violation(°)	10.6
Max. distance constraint violation (Å)	0.37
Deviations from idealized geometry
Bond length (Å)	0.007 ± 0.0001
Bond angle (°)	1.40 ± 0.01
Impropers (°)	1.05 ± 0.01
Average pairwise r.m.s.d. of heavy atoms (Å)
G-tetrads	1.01 ± 0.12
With C20	1.14 ± 0.14
With C4,G5,C6	1.04 ± 0.12
With A10,T15	1.13 ± 0.14
All residues	2.55 ± 0.65

^aThe ensemble of 10 structures is selected based both on the minimal energy terms and number of NOE violations.