Table 1.
Currently known P-glycoprotein substrate drugs
| Chemotherapeutics | Cardiac Drugs |
|---|---|
| Doxorubicin | Digoxin |
| Mitoxantrone | Diltiazem |
| Paclitaxel | Losartan |
| Vinblastine | Quinidine |
| Vincristine | Verapamil |
| Antimicrobials/Antifungals | Steroids |
| Doxycycline | Aldosterone |
| Erythromycin | Cortisol |
| Itraconazole | Dexamethasone |
| Ketoconazole | Estradiol |
| Rifampin | Hydrocortisone |
| Tetracycline | Methylprednisolone |
| Immunosuppressants | Miscellaneous |
| Cyclosporin A | Amitriptyline |
| Tacrolimus | Butorphanol |
| Antiemetics | Ivermectin |
| Domperidone | Morphine |
| Ondansetron | Moxidectin |
| H1-antihistamines | Phenothiazines |
| Fexofenadine | Phenytoin |
| Terfenadine | Selamectin |
| H2-antihistamines | |
| Cimeditine | |
| Ranitidine |