Table 2.
Significant linkages to known retinal disease genes
| Gene | Probe ID | Marker | P value |
|---|---|---|---|
| Abca4 | 1384603_at | D2Rat55 | 3.0E-04 |
| Aipl1 | 1387166_at | D10Mgh6 | 6.9E-11 |
| Bbs1 | 1383417_at | D1Rat112 | 1.9E-10 |
| Bbs4 | 1383007_at | D8Rat141 | 4.3E-05 |
| Bbs8 | 1378416_at | D8Rat46 | 4.6E-04 |
| Ca4 | 1368437_at | D10Mgh6 | 2.0E-04 |
| Cacna1f | 1387846_at | DXRat40 | 2.4E-06 |
| Cacna1f | 1387846_at | DXRat38 | 6.6E-09 |
| Grk1 | 1369257_at | D14Rat94 | 1.9E-04 |
| Jag1 | 1368725_at | D3Rat26 | 4.4E-04 |
| Lrp5 | 1380242_at | D15Rat40 | 8.1E-04 |
| Opn1 sw | 1388025_at | D10Rat27 | 8.0E-07 |
| Opn1 sw | 1388025_at | D15Mit2 | 1.1E-06 |
| Pcdh15 | 1378408_at | D6Mit3 | 2.0E-04 |
| Pde6a | 1393426_at | D18Rat51 | 0.0 |
| Pex1 | 1376595_at | D3Rat70 | 5.5E-04 |
| Pex7 | 1379784_at | D1Rat3 | 1.3E-04 |
| Pex7 | 1379784_at | D8Mit5 | 9.6E-05 |
| Rbp4 | 1371762_at | D1Rat119 | 2.6E-07 |
| Rdh12 | 1382949_at | D1Rat97 | 4.0E-04 |
| Rdh5 | 1379587_at | D7Rat154 | 0.0 |
| Rdh5 | 1379587_at | D2Mit5 | 4.2E-04 |
| Rs1 | 1396807_at | D20Rat21 | 2.8E-04 |
| Tead1 | 1389287_at | D4Rat61 | 4.1E-04 |
| Tead1 | 1389287_at | DXRat40 | 5.9E-04 |
| Timm8a | 1368400_at | DXRat73 | 1.8E-05 |
| Timm8a | 1368400_at | D11Mgh5 | 2.5E-04 |
| Timm8a | 1368400_at | D8Mit5 | 7.1E-04 |
| Tulp1 | 1393071_at | D1Rat371 | 6.9E-04 |
For each linked region, the genetic marker with the most significant P value is shown. A Bonferroni-adjusted P value of 0.05 was used based on correction for the number of genes tested.