TABLE 1.
Hematopoietic indices of mutant micea
| Mouse (n) | Hb (g/dl) | Ht (%) | MCV (fl) | MCH level (pg) | WBC count (/μl) | Plt count (104/μl) |
|---|---|---|---|---|---|---|
| Wild type (24) | 13.7 ± 0.8 | 43.7 ± 2.5 | 49.8 ± 2.5 | 15.8 ± 1.0 | 7,917 ± 2,773 | 63.2 ± 16.9 |
| Heterozygously transgenic (25) | 14.1 ± 1.0 | 46.2 ± 4.1 | 50.8 ± 2.1 | 15.4 ± 0.8 | 8,116 ± 3134 | 67.5 ± 15.3 |
| Homozygously transgenic (25) | 9.0 ± 1.8* | 28.8 ± 6.0* | 72.2 ± 4.7* | 22.7 ± 2.2* | 9,428 ± 3,027 | 180.0 ± 48.6* |
a
Transgenic mice 6 to 12 weeks of age were used. Age-matched wild type BDF-1 mice were used as controls. Values are means ± standard errors of the means. *, P < 0.001 compared with wild-type and homozygously transgenic mice. Abbreviations: Hb, hemoglobin; Ht, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; WBC, white blood cell; Plt, platelet.