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. 2006 Aug 28;26(21):8191–8201. doi: 10.1128/MCB.00242-06

FIG. 3.

FIG. 3.

Mir-17-5p suppresses ER-mediated signaling. (A) Luciferase activity in CHO-K1 cells transiently transfected with an ER expression vector, a luciferase reporter plasmid, and 2′-O-methyl Mir17p or Mir-95, in the absence or presence of 10 nM E2. The data shown are means of triplicate experiments, and error bars indicate the standard deviations. (B) Luciferase activity in cells cotransfected with AIB1-expressing reporter plasmids containing wild-type (AIB3′UTR) or mutant (AIBm3′UTR) AIB1 3′UTRs, ER, ERE-Luc, and 2′-O-methyl Mir-17-5p or 2′-O-methyl Mir-95. The data shown are means of triplicate experiments, and error bars indicate the standard deviations.