TABLE 1.
Genotype and phenotype distribution of E13.5 to E16.5 embryos derived from YB-1+/− MSY4+/− intercrosses
| Genotype (YB-1; MSY4) | Predicted % frequency of total | No. of embryos recovered (% frequency of total) | Phenotype frequency (% embryos of the same genotype)
|
||
|---|---|---|---|---|---|
| Death | Alive and runting | Alive and exencephaly | |||
| −/−; +/+ | 6.25 | 5 (6.4) | 0 | 3/5 (60) | 1/5 (20) |
| −/−; +/− | 12.5 | 4 (5.1) | 1/4 (25) | 2/4 (50) | 0 |
| −/−; −/− | 6.25 | 8 (10.3) | 7/8 (87.5) | 1/8 (12.5) | 1/8 (12.5) |
| +/+; +/+ | 6.25 | 5 (6.4) | 0 | 0 | 0 |
| +/+; +/− | 12.5 | 8 (10.3) | 0 | 0 | 0 |
| +/+; −/− | 6.25 | 4 (5.1) | 0 | 0 | 0 |
| +/−; +/+ | 12.5 | 11 (14.1) | 0 | 0 | 0 |
| +/−; +/− | 2.5 | 25 (32.0) | 0 | 1/25 (4) | 0 |
| +/−; −/− | 12.5 | 8 (10.3) | 0 | 0 | 0 |