FIG. 7.
Examples of TRE5-A integrations upstream of an inactivated tRNA gene equipped with a downstream extra B box. DNA sequences of representative TRE5-A insertions at positions 10 bp (A) and 50 bp (B) upstream of an inactive ValUAC(C56G) are shown. The intron sequence is shown in lowercase letters. The exB box is presented in uppercase letters inside the black box; the mutated B box of the tRNA gene is boxed with a dashed line. The tRNA gene sequence is shown in uppercase letters. The insertion site is indicated by the vertical arrow. The DNA sequences of the inserted TRE5-As are shown in bold uppercase letters. The first nucleotides of the 5′-deleted TRE5-As are shown in parentheses and TSDs in gray boxes.