TABLE 2.
SS-MO hypomorphs with abnormal hearts have slowed heartbeatsa
| Age (hpf) | Avg no. of heartbeats/min (SD)
|
% of control (SD, no. of independent trials) | |
|---|---|---|---|
| MO injected | Control | ||
| 48 | 90 (8) | 155 (15) | 60 (1, 3) |
| 72 | 95 (6) | 170 (15) | 57 (8, 3) |
a
Embryos were injected with 1.5 pmol of SS-MO directed against splice sites 1 to 3 and examined microscopically at 48 or 72 hpf. These data are averages of measurements from 10 embryos in each group. The heartbeat rate was determined three times for each embryo.