Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Sep 25;26(23):8880–8891. doi: 10.1128/MCB.00751-06

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2006, American Society for Microbiology

PMC Copyright notice

FIG. 6. — Characterization of the cell cycle progression in S6^wt^/^del/p53⁻^/⁻ embryos. (A) Western blot analysis of lysates prepared from E10.5 S6^wt^/^wt/p53⁻^/⁻ and S6^wt^/^del/p53⁻^/⁻ embryos using antibodies against the indicated cell cycle regulators. Cyc, cyclin. (B) Quantitative RT-PCR analysis of cyclin D1 and cyclin D3 mRNAs expression in E10.5 S6^wt^/^wt/p53⁻^/⁻ (black bars) and S6^wt^/^del/p53⁻^/⁻ (gray bars) embryos. (C) Sagittal sections of the entire E11.5 embryos of indicated genotypes were stained with anti-BrdU antibody. Fetal livers are indicated by arrows. (D) BrdU incorporation in roofs of midbrain (RM) and fetal livers (FL) of the indicated genotypes (higher magnification of embryo sections from panel E). Scale bar, 100 μm. (E) Lysates of E12.5 fetal livers or the remaining parts of the embryo were analyzed by Western blotting employing antibodies against the indicated proteins. S6^wt^/^wt/p53⁻^/⁻ and S6^wt^/^del/p53⁻^/⁻ genotypes in panels A and E are indicated with 1 and 2, respectively.