FIG. 2.

CaMKKα KO mice performed similarly to WT littermates on several aspects of the Morris water navigation task. (A and B) Performance in terms of path length is depicted for the cued trials and for acquisition during the place condition as a function of blocks of trials. No differences were found between the groups at any point during either of the two tasks. (C and D) Retention performance on probe trials. No differences were found between KO and WT mice in terms of the amount of time the mice spent searching in the quadrant where the platform used to be located (target quadrant time [C]) or in the number of times the mice swam over the former platform location (platform crossings [D]). In panel C, the broken line represents the amount of time spent in the target quadrant that would be expected on the basis of chance alone.