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. Author manuscript; available in PMC: 2007 Nov 10.
Published in final edited form as: Biochem Biophys Res Commun. 2006 Sep 18;350(1):233–237. doi: 10.1016/j.bbrc.2006.09.036

Fig. 1.

Fig. 1

Effect of HO-1 gene deletion on vulnerability of astrocytes and neurons to Hb. A) Mean medium LDH (± S.E.M., 14–20/condition) in astrocyte cultures treated for 75–120 h with indicated concentrations of Hb. LDH values were scaled to those in sister cultures treated with 0.3% Triton X-100 (= 100), which produces 100% cell lysis. B) Mixed neuron/astrocyte cultures (27–31/condition) were treated with indicated Hb concentrations for 24h. LDH values were scaled to those in sister cultures treated with 300 μM NMDA, which releases all neuronal LDH without injuring astrocytes. *** P < 0.001 versus signal in corresponding WT culture, Bonferroni multiple comparisons test.