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The structure of the full-length trf2 gene, transcript, and protein products. (A) The structure of trf2 and isolated transcripts. Coding regions are shown as filled boxes, and noncoding ones are indicated with open boxes. (B) The predicted structure of the TRF2 long form; the short TRF2 described earlier (41) is shown below. The TBP-homology domain, two coiled coils, nuclear localization signals (NLS), and the regions used to raise antibodies are indicated.
