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siRNA silencing of TReP-132 abolishes inhibition of T47D cell proliferation by progesterone but not by rosiglitazone. T47D cells, treated with or without progesterone (A) (30 nM) or rosiglitazone (B) (0.5 μM) and transfected with control or TReP-132 siRNAs (700 ng) at 0 and 3 days, were harvested at 2, 4, or 6 days for measure of DNA content. ns, not significant; *, P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001 versus control.
