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The non-significant (Drug A) and significant (Drug B) relationships between the drug clearance (CL) and the patient creatinine clearance (CLCR) in a small population of sixteen patients for two hypothetical drugs. Drug A: CL = (0.484 × CLCR) +1.64, p > 0.05, r2 = 0.054; Drug B: CL = (2.47 × CLCR) +3.74, p < 0.05, r2 = 0.50.
