Skip to main content
. Author manuscript; available in PMC: 2006 Nov 16.
Published in final edited form as: Immunol Rev. 2006 Oct;213:36–47. doi: 10.1111/j.1600-065X.2006.00436.x

Fig. 2. Soluble products of the fetal placenta drive tolerance in the pregnant uterus.

Fig. 2

The fetal placenta is directly apposed and is in contact with the decidua throughout pregnancy. Placental cells, mainly vCTB and sTB within the villi, synthesize soluble substances that program maternal immune cells in the adjacent decidua. Not shown in this figure are the substances on trophoblast cell membranes that have complementary functions.