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. Author manuscript; available in PMC: 2006 Nov 16.
Published in final edited form as: Immunol Rev. 2006 Oct;213:36–47. doi: 10.1111/j.1600-065X.2006.00436.x

Fig. 5. An illustration of the inhibitory members of the LILR family.

Fig. 5

The inhibiting LILRs lack the arginine residue that is characteristic of the activating members of this family and have varying configurations of the extracellular portions of the molecules. LILRB1 (ILT2), LILRB2 (ILT4), and LILRB3 through B5 have long cytoplasmic tails with two to four immunoreceptor tyrosine-based inhibitory motif domains of varying sequences. Leukocytes express one or more of the LILRB receptors. Modified from Brown et al.(66).