Table 2.

Inflammatory cytokine and chemokine concentrations in airways from CF and wild-type (WT) mice in the absence of induction with P aeruginosa LPS, with and without pre-treatment with azithromycin (10 mg/kg/day), by oral administration, for 4 weeks.

		MIP-2 pg/ml	TNF-α pg/ml	IL-10 pg/ml
CF	AZM-	4.9 ± 0.4	11.8 ± 1.8	84.2 ± 13.9
	AZM+	5.4 ± 0.7	9.3 ± 1.6	68.1 ± 7.9
WT	AZM-	2.9 ± 0.3	8.1 ± 1.6	42.3 ± 12.1
	AZM+	3.7 ± 0.4	10.6 ± 2.1	103.0 ± 19.1*

Values are means ± SEM for 9–13 animals per each of the 4 subgroups from pooled data obtained from the same sets of experiments as those used to generate Table 1. * p < 0.025 for comparison of corresponding mean value vs. that obtained for the same parameter in the same group of animal without pre-treatment with azithromycin.